Methods and compositions for treating neurodegenerative diseases
AssigneeAugusta University Research Institute, Inc.
InventorsRobert Yu, Yutaka Itokazu
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Abstract
Methods and compositions for treating neurodegenerative diseases are provided. In one embodiment, the method includes administering gangliosides into the brain of a mammal in need of such treatment. The gangliosiges are preferably GM1 and GD3 gangliosides. The gangliosides are intranasally administered in an amount effective to delay and/or prevent disease progression, and to increase the resilience of brains by promoting adult neurogenesis by gangliosides.
Claims19
A method for treating one or more of the symptoms or processes of neurodegeneration in a subject in need thereof comprising intranasally administering to the subject an effective amount of ganglioside GD3.
A method of treating neurodegeneration and/or neurological injury of the eye(s) of a subject in need thereof comprising administering an effective amount of ganglioside GD3, and optionally administering an effective amount of ganglioside GM1, into the eye(s) of the subject.
Dependencies are inferred from the claim text.