Use of atractylenolide I in preparation of medicine for preventing and/or treating cervical cancer
AssigneeJiangsu Province Hospital of Chinese Medicine
InventorsYue Han, Qingling Ren
Life of this patent
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Abstract
A compound represented by formula I, or a salt thereof, or a stereoisomer thereof, or a solvate thereof, or a hydrate thereof can be used in the preparation of a medicine for preventing and/or treating cervical cancer. The compound is preferably atractylenolide I of the combination of atractylenolide I and a P2X7R antagonist can be used in the preparation of a medicine for preventing and/or treating cervical cancer. Meanwhile, for inhibition of the proliferation of SiHa cells, atractylenolide I and the P2X7R antagonist are combined for use to achieve a synergistic effect.
Claims7
A pharmaceutical composition for treating cervical cancer, comprising atractylenolide I or a salt thereof, and a P2X7R antagonist, wherein the P2X7R antagonist is BzATP, and
- a molar ratio of atractylenolide I or the salt thereof to the P2X7R antagonist is (1-10):
- 1.
Dependencies are inferred from the claim text.