Composition and method to reduce liver fat and circulating triacylglycerols
OwnerRobert R. Wolfe, Melanie Giselle Cree +1inventors
InventorsRobert R. Wolfe, Melanie Giselle Cree, Frederick L. Wolfe
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Abstract
The present invention relates to amino acid compositions and methods to reduce liver fat and circulating concentration of triacylglycerol. The invention further relates to amino acid compositions for reducing liver fat and circulating triacylglycerol (TG) in individuals with hepatic steatosis (HS). The compositions described herein are pharmaceutical or nutritional compositions. The compositions are based on a specially formulated mixture of essential amino acids (EAAs).
Claims20
A composition to reduce liver fat and circulating concentration of triacylglycerol comprising an amount of the free essential amino acids (EAAs) composition, wherein the EAAs composition consists of from about 30% to about 34% leucine, from about 9 to about 13% valine, from about 9 to about 13% isoleucine, from about 8 to about 12% histidine, from about 8 to about 12% phenylalanine, from about 14 to about 18% lysine, and from about 8 to about 12% threonine of the EAAs composition by weight.
A method of reducing liver fat and circulating concentration of triacylglycerol comprising administering a free essential amino acids (EAAs) composition, wherein the EAAs composition consists of from about 30% to about 34% leucine, from about 9 to about 13% valine, from about 9 to about 13% isoleucine, from about 8 to about 12% histidine, from about 8 to about 12% phenylalanine, from about 14 to about 18% lysine, and from about 8 to about 12% threonine of the EAAs composition by weight.
A method of reducing liver fat and circulating concentration of triacylglycerol comprising administering a free essential amino acids (EAAs) composition, wherein the EAAs composition consists of 32% leucine, 11% valine, 11% isoleucine, 10% histidine, 10% phenylalanine, 16% lysine, and 10% threonine in free form of the EAAs composition by weight.
Dependencies are inferred from the claim text.