Pharmaceutical formulation
OwnerLarry P. Bleierinventor
Life of this patent
Estimating the term…
Abstract
A pharmaceutical formulation for topical dental administration or medical (e.g., implant) treatment, including effective amounts of: at least one antimicrobial compound; at least one peroxide source compound; and at least one gel agent. Also disclosed are methods of oral anatomy treatment. The pharmaceutical formulation and treatment methods provide the patient with oral anatomy benefits including, for example, decreased or arrested gum recession; decreased or arrested bone recession; decreased or arrested bone mass loss; decreased or eliminated pain; decreased or eliminated bleeding; decreased or eliminated swelling; enhanced regeneration of bone; enhanced soft tissue repair; or a combination thereof.
Claims14
A method of conditioning a wound including a wound surface, comprising:
- chemically debriding the wound by applying a pharmaceutical formulation directly to the wound surface with a dental or medical instrument to chemically anesthetize the wound surface;
- wherein the instrument is selected from the group consisting of a probe, a curette, and a scaler;
- and
- wherein the pharmaceutical formulation comprises:
- a tetracycline antimicrobial compound, a salt thereof, a prodrug thereof, in from 25 to 30 weight % of the total weight of the formulation;
- at least one peroxide source compound in an effective amount from 1.5 to 44 weight % of the total weight of the formulation;
- and
- at least one gel agent in an effective amount from 1.0 to 90 weight % of the total weight of the formulation.
A method of conditioning a wound including a wound surface, comprising:
- mechanically debriding the wound surface with a pharmaceutical formulation, the mechanical debriding including scraping the wound surface with an instrument including a working edge by contacting the wound surface that includes the pharmaceutical formulation directly with the working edge to finish the wound surface to form a wound surface roughness of 1 to 50 microns;
- wherein the pharmaceutical formulation comprises:
- a tetracycline antimicrobial compound, a salt thereof, a prodrug thereof, in from 25 to 30 weight % of the total weight of the formulation;
- at least one peroxide source compound in an effective amount from 1.5 to 44 weight % of the total weight of the formulation;
- and
- at least one gel agent in an effective amount from 1.0 to 90 weight % of the total weight of the formulation.
Dependencies are inferred from the claim text.