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US 12,740,703 B2Granted
Optical microscope for retinal imaging
AssigneeElectronics and Telecommunications Research Institute
InventorsSang Kyun Lee, Dong Hoon Song, Chul Huh
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AssigneeElectronics and Telecommunications Research Institute
InventorsSang Kyun Lee, Dong Hoon Song, Chul Huh
Estimating the term…
The present invention proposes a technology that enables in vivo imaging while expanding the penetration depth of light into the tissue in an ultrasound-induced optical clearing microscopy (USOCM) system using an optical microscope, in particular, a non-linear optical microscope such as a two-photon microscope, and an ultrasonic transducer. For maximum efficiency, the ultrasonic transducer should be positioned between an optical microscope (objective lens) and the sample. In this case, since an existing ultrasonic transducer is opaque, a laser beam of an optical microscope using an ultrashort laser system cannot pass through the existing ultrasonic transducer. In order to solve such a problem, a transparent ultrasonic transducer is applied such that there is no problem in a laser beam passing therethrough and reaching a sample.
An optical microscope for radiating a laser beam onto a sample and observing the sample through an objective lens, the optical microscope comprising a transparent ultrasonic transducer which radiates ultrasonic waves onto the sample and through which the laser beam passes,
A transparent ultrasonic transducer which is used in an optical microscope for radiating a laser beam onto a sample and observing the sample through an objective lens, generates ultrasonic waves to radiate the generated ultrasonic waves onto the sample, and allows the laser beam to be transmitted, the transparent ultrasonic transducer comprising an acoustic lens that allows acoustic focusing of the ultrasonic waves to be performed with respect to the sample,
Dependencies are inferred from the claim text.