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AssigneesOklahoma Medical Research Foundation, The Board of Regents of the University of Oklahoma
InventorsA. Darise Farris, Sherri Longobardi
Estimating the term…
The present invention includes a method and kit of determining that a patient negative for anti-Ro autoantibodies has Sjögren's syndrome (SS) without performing a lip biopsy comprising: obtaining a liquid biological sample from the patient suspected of having SS: determining that the patient is negative for anti-Ro autoantibodies; and detecting autoantibodies to 1, 2, 3, 4, 5, 6, 7, 8, or 9 proteins selected from: CCDC155, DDB1, MUM1L1, NFU1, RPS29, SOX5, TCP10, ZNF655, or RPAP3, which indicate(s) that the patient has SS. Also, a lack of certain autoantibodies such as KCNAB1, KCNAB2, or as listed in Table 1, Table 2, or Table 3, and FIG. 11 or 16 in Ro neg cases may be used to detect SS.
A method of determining that a patient negative for anti-Ro autoantibodies has Sjogren's syndrome (SS) without performing a lip biopsy comprising:
A method of determining that a patient negative for Ro autoantibodies has Sjögren's syndrome (SS) without performing a lip biopsy comprising:
A method of determining that a patient negative for Ro autoantibodies has Sjögren's syndrome (SS) without performing a lip biopsy comprising:
Dependencies are inferred from the claim text.