Alkoxyphenyl derivatives, protected nucleosides and protected nucleotides, method for producing oligonucleotides, and method for removing substituents

A compound of general formula (3) or a derivative thereof:

• wherein:
• R each independently is an optionally substituted alkyl group having 10 to 40 carbon atoms;
• m is an integer between 1 and 5, wherein if m is 2 or more, a plurality of ROs may be the same or different;
• X is O, or S;
• n is an integer from 1 to 4;
• Y is the following general formula (4) or general formula (5):
• wherein for formula (4):
• Base is a nucleobase which may be modified, wherein if 2 or more Bases are present, a plurality of Bases present may be the same or different;
• B is a hydrogen atom, an optionally protected hydroxyl group, or a halogen, wherein if 2 or more Bs are present, a plurality of Bs present may be the same or different;
• W is a hydrogen atom or protecting group;
• R4 is an alkyl group having 1 to 4 carbons and having an electron withdrawing group, wherein if 2 or more R4s are present, a plurality of R4s present may be the same or different;
• Z represents is O or S, wherein if 2 or more Zs are present, a plurality of Zs present may be the same or different;
• y1 is any integer greater than or equal to 0;
• and * is a bonding position in the above general formula (3);
• wherein for formula (5):
• Base is a nucleobase which may be modified, wherein if 2 or more Bases are present, a plurality of Bases present may be the same or different;
• Q is a hydrogen atom or protecting group;
• V is an alkoxy group having 1 to 6 carbon atoms, a di(C-alkyl)amino group, or a piperazino group in which the nitrogen atom at the 4-position is protected with a protecting group and may be further substituted, wherein if 2 or more Vs are present, a plurality of Vs present may be the same or different;
• y2 is any integer greater than or equal to 0;
• and * is a bonding position in the above general formula (3).