Transition metal complex containing tetradentate nitrogen donor ligand and electrochemical biosensor comprising same

A electrochemical blood glucose sensor comprising a transition metal complex, wherein the transition metal complex comprises a tetradentate nitrogen donor ligand represented by Chemical formula 1 or 2 below, as an electron transfer mediator:

• in the Chemical formula 1 or Chemical formula 2,
• M is Os;
• and
• Ca, Cb, Cc are heterocyclic compounds comprising one or more nitrogen atoms, and are linked to an amine group and a methylene group at the position 2 of the cyclic compound;
• and
• Lm1 and Lm2 are each independently —H, —F, —Cl, —Br, —I, —NO2, —NCCH3, —CO, —OH2, —NH3 or a heterocyclic compound comprising one or more nitrogen atoms;
• Lb-Lb is catechol, acetylacetone, 2-picolinic acid, 2-pyridinecarboxamide, 2,2-bipyridine or 2,2-bithiazole;
• m is a negative charge from −1 to −5 or positive charge from +1 to +5;
• and
• R1, R2 and R3 are each independently —H;
• —F;
• —Cl;
• —Br;
• —I;
• —NO2;
• —CN;
• —CO2H;
• —SO3H;
• —NHNH2;
• —SH;
• —OH;
• —NH2;
• —CH2OH;
• —CONHCH2CH2NH2;
• or substituted or unsubstituted alkoxycarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkoxy, alkylamino, dialkylamino, alkanylamino, arylcarboxyamido, hydrazino, alkylhydrazino, hydroxyamino, alkoxyamino, alkylthio, alkenyl, aryl or alkyl;
• and
• X is a counter ion;
• and
• n means the number of counter ions, and is within the integer range 1 to 5.