PAI-1 inhibitors and uses thereof

A compound of formula (Ia):

• or a pharmaceutically acceptable salt thereof, wherein:
• R2 is H, halo, C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkynyl, C1-C4 alkoxy, C1-C4 haloalkyl, or C1-C4 haloalkoxy;
• R3 is H, halo, or C1-C4 alkyl;
• wherein R2 and R3 are optionally taken together with the carbon atoms to which they are attached to form a 5-or 6-membered ring optionally substituted with 1 or 2 substituents independently selected from C1-C4 alkyl, halo, and oxo;
• X6 is CR6 or N;
• R6 is H, halo, or C1-C4 alkyl;
• and
• R8 is a group of formula:
• wherein Rx is —(CH2)n—Y or a monocyclic heterocyclyl having 1 or 2 heteroatoms independently selected from O and N, wherein the monocyclic heterocyclyl is unsubstituted or substituted with 1 C1-C4 alkyl group, wherein n is 1 or 2, and Y is selected from —COORg and —NRhRi, wherein Rg, Rh, and Ri are each independently selected from H and C1-C4 alkyl.