Antimicrobial susceptibility testing device, antimicrobial susceptibility testing method using the testing device and system including the testing device
AssigneeQuantamatrix Inc.
InventorsJung Il Choi, Sun Jae Hwang
Life of this patent
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Abstract
An antimicrobial susceptibility testing device according to an embodiment of the present invention includes a substrate and a driving unit rotating the substrate. The substrate includes first injection holes formed so as to penetrate the upper surface thereof and channels forming passages therein through which antibiotics, a bacteria sample or mixed solutions thereof injected through the first injection holes are movable and having first regions where the mixed solutions are concentrated and localized by centrifugal force applied when the substrate is rotated by the driving unit.
Claims15
An antimicrobial susceptibility testing device comprising a substrate and a driving unit rotating the substrate,
- wherein the substrate comprises first injection holes formed so as to penetrate the upper surface thereof and channels forming passages therein through which antibiotics, a bacteria sample or mixed solutions thereof injected through the first injection holes are movable and having first regions where the mixed solutions are concentrated and localized by centrifugal force applied when the substrate is rotated by the driving unit,
- wherein each of the channels has a second region comprising a section whose width becomes narrower toward the first region such that the mixed solutions are localized in the first region, and
- wherein each of the channels has a third region comprising a section whose width becomes narrower toward the second region such that the mixed solutions are transferred to the second region when the applied centrifugal force is equal to or greater than a reference value.
An antimicrobial susceptibility testing method comprising:
- injecting antibiotics into channels formed in a substrate and drying the antibiotics;
- mixing a bacteria sample with the dried antibiotics injected into the channels;
- and rotating the substrate to apply centrifugal force to the mixed solutions of the antibiotics and the bacteria sample such that the mixed solutions are localized in first regions of the channels,
- wherein each of the channels has a second region comprising a section whose width becomes narrower toward the first region such that the mixed solution is localized in the first region, and
- wherein each of the channels has a third region comprising a section whose width becomes narrower toward the second region such that the mixed solution is transferred to the second region when the applied centrifugal force is equal to or greater than a reference value.
An antimicrobial susceptibility testing system comprising a substrate, a driving unit rotating the substrate, an image capture unit capturing images of first regions of the substrate, and an image processing unit processing the images captured by the image capture unit wherein the substrate has injection holes formed so as to penetrate the upper surface thereof and channels forming passages therein through which antibiotics, a bacteria sample or mixed solutions thereof injected through the injection holes are movable and having first regions where the mixed solutions are concentrated and localized by centrifugal force applied when the substrate is rotated by the driving unit,
- wherein each of the channels has a second region comprising a section whose width becomes narrower toward the first region such that the mixed solution is localized in the first region, and
- wherein each of the channels has a third region comprising a section whose width becomes narrower toward the second region such that the mixed solution is transferred to the second region when the applied centrifugal force is equal to or greater than a reference value.
Dependencies are inferred from the claim text.