Devices and methods for precision dose delivery

A drug delivery device, comprising:

• a body storing a dose of medicament;
• a flange coupled to the body, the flange including a sidewall, a channel defined by the sidewall, and a pair of grooves formed along an interior of the sidewall;
• and
• a plunger rod coupled to the flange and at least partially disposed within the body, the plunger rod including a proximal end and a pair of extensions extending distally from the proximal end;
• wherein the plunger rod is configured to prime the drug delivery device by moving a first stroke relative to the flange, thereby positioning the pair of extensions against the sidewall;
• and
• wherein the plunger rod is configured to prepare the drug delivery device for delivering the dose of medicament by rotating relative to the flange, thereby generating a user feedback as the pair of extensions expand radially-outward from a compressed state to an extended state upon engaging the pair of grooves.

A drug delivery device, comprising:

• a body;
• a flange coupled to the body, the flange including a collar having a channel and a pair of grooves positioned along opposite sides of the channel;
• and
• a plunger rod coupled to the flange with the channel configured to accept the plunger rod, the plunger rod including a proximal portion and a pair of extensions extending distally from opposite sides of the proximal portion;
• wherein the plunger rod is longitudinally moveable and rotatable relative to the flange, wherein the plunger rod is configured to:
• move distally relative to the flange by an initial stroke to prime the drug delivery device, wherein the pair of extensions are radially misaligned with and positioned outside of the pair of grooves as the plunger rod moves the initial stroke;
• rotate relative to the flange to prepare the drug delivery device for delivering a dose of medicament from the body, wherein the pair of extensions radially align with and contact the pair of grooves, thereby generating an audible feedback, as the plunger rod rotates relative to the flange;
• and
• move distally relative to the flange by a final stroke to deliver the dose of medicament from the drug delivery device, wherein the pair of extensions are maintained inside and in contact with the pair of grooves as the plunger rod moves the final stroke.