Adhesive devices and uses thereof

A method for reversibly stabilizing bone fragments in a body, the method comprising:

• (i) forming a first reversible anchor on a first bone fragment by (a) heating an adhesive composition to form a softened adhesive composition and contacting the softened adhesive composition to the first bone fragment, and (b) permitting the softened adhesive composition to cool to form the first anchor affixed to the first bone fragment;
• (ii) forming a second reversible anchor on a second bone fragment by (a) heating an adhesive composition to form a softened adhesive composition and contacting the softened adhesive composition to the second bone fragment, and (b) permitting the softened adhesive composition to cool to form the second anchor affixed to the second bone fragment;
• wherein the heating comprises applying ultrasonic energy using an ultrasonic welder at a frequency of from 35 kHz to 70 KHz;
• wherein the adhesive composition comprises hydroxyapatite as a heat transfer agent, a filler comprising polycaprolactone (PCL), polydioxanone (PDX), poly(lactic-co-glycolic acid) (PLGA), or poly-3-hydroxybutyrate (P3HB), hydroxyapatite (HA), or a copolymer thereof, or a blend thereof, and the adhesive composition has a tackifying temperature from 40° C. to 55° C., and
• wherein the first anchor and the second anchor are connected to a support structure for stabilizing the bone fragments;
• and
• wherein the adhesive composition is not dependent upon in situ curing reactions for adhesion.