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US 12,734,237 B2Granted
Formulation comprising anti-IL-23P19 antibody, method for preparing same and use thereof
AssigneeInnovent Biologics (Suzhou) Co., Ltd.
InventorsWei Cao, Liqiang Ma, Yinjue Wang, Kaisong Zhou
Life of this patent
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Abstract
The present invention relates to a formulation comprising an anti-IL-23p19 antibody, and in particular to a pharmaceutical formulation comprising an anti-IL-23p19 antibody, a buffer, a stabilizer and a surfactant. Furthermore, the present invention further relates to therapeutic or prophylactic use of these formulations.
Claims23
A liquid antibody formulation, comprising:
- (i) an anti-IL-23p19 antibody;
- (ii) a buffer,
- (iii) a stabilizer, and
- (iv) a surfactant,
- wherein the anti-IL-23p19 antibody comprises the following 6 CDRs:
- a heavy chain VH CDR1 of
- (SEQ ID NO:
- 1)
- GYTFTSYLMH;
- a heavy chain VH CDR2 of
- (SEQ ID NO:
- 2)
- YINPYNEGTN;
- a heavy chain VH CDR3 of
- (SEQ ID NO:
- 3)
- NWDLPY;
- a light chain VL CDR1 of
- (SEQ ID NO:
- 4)
- RASQSISDYLH;
- a light chain VL CDR2 of
- (SEQ ID NO:
- 5)
- YASQSMS;
- and
- a light chain VL CDR3 of
- (SEQ ID NO:
- 6)
- QQGHSFPFT,
- and the boundaries of the CDRs are determined as per the AbM scheme.
28 more elements
Dependencies are inferred from the claim text.