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US 12,734,228 B2Granted
Protective vaccine antigen against streptococcal infection
AssigneeThe Regents of the University of California
InventorsDavid J. Gonzalez, Anaamika Campeau, Dominic M. McGrosso
Life of this patent
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Abstract
Group A Streptococcus (GAS) is associated with an estimated half-million deaths per year and 21 severe autoimmune sequalae. Despite the ubiquity of GAS infection, no vaccine currently exists. Provided herein is a Streptococcus S protein or an equivalent thereof used as a vaccine, along with the related compositions and methods.
Claims11
A method of treating or protecting against a Group A Streptococcus (GAS) infection in a subject in need thereof, comprising administering to the subject an effective amount of
- an isolated Streptococcus(S) protein comprising SEQ ID NO:
- 1 or an equivalent thereof having at least 95% sequence identity to SEQ ID NO:
- 1,
- thereby treating or protecting against the GAS infection in the subject.
1 more element
Dependencies are inferred from the claim text.