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US 12,734,215 B2Granted
Biased IL2 muteins methods and compositions
AssigneeSynthekine, Inc.
InventorsJan Emmerich, Steve Kauder, Scott Alan McCauley, Martin Oft
Life of this patent
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Abstract
The present disclosures related to human interleukin-2 (hIL2) muteins, pharmaceutical formulations thereof, methods for preparing interleukin-2 muteins, recombinant vectors and cells comprising nucleic acids encoding IL2 muteins and methods for the treatment of human disease.
Claims38
A method of treating a human subject suffering from cancer, the method comprising,
- administering to said subject a pharmaceutical formulation comprising a polypeptide comprising SEQ ID NO:8, wherein the administering ameliorates one or more symptoms associated with the cancer.
Dependencies are inferred from the claim text.