Combined formulation capable of ameliorating gastrointestinal adverse effects caused by oxaliplatin and preparation method therefor and use thereof

Abstract

Disclosed in the present invention is a combined formulation capable of ameliorating gastrointestinal adverse effects caused by oxaliplatin, which comprises Lycium barbarum polysaccharides and Akkermansia muciniphila; the Lycium barbarum polysaccharide is obtained by removing small molecular substances by ethanol extraction, then continuously performing reflux extraction by using water, and separating by using a hollow fiber ultrafiltration device; Akkermansia muciniphila is Akkermansia muciniphila ATCC BAA835; the combined formulation provided by the present invention can ameliorate intestinal injury, reduce inflammatory factors and maintain intestinal barriers, and thus can be used as a functional food or a medicine to ameliorate gastrointestinal adverse effects caused by oxaliplatin.

Dependencies are inferred from the claim text.