Compositions and methods for increasing T cell function
AssigneesSociete des Produits Nestle S.A., Ludwig Institute for Cancer Research
InventorsNicola Vannini, George Coukos, Serge Andre Dominique Rezzi, Julie Laval, Caroline Monnard, Marcela Rincon Restrepo
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Abstract
An agent for use in reducing T cell exhaustion and/or increasing T cell function, and/or boosting immunity, wherein the agent is selected from the group consisting of nicotinamide riboside, vitamin B12, a urolithin, manganese, serine, glycine, arginine, asparagine, and a combination of two or more thereof.
Claims10
A method for treatment of (a) a bacterial or viral infection or (b) cancer that is at least one of a lymphoma, multiple myeloma or a leukaemia, the method comprising administering an effective amount of a composition comprising a) nicotinamide riboside, a urolithin and manganese;
- (b) nicotinamide riboside, vitamin B12 and manganese;
- (c) nicotinamide riboside, a urolithin and vitamin B12;
- or (d) nicotinamide riboside, vitamin B12, a urolithin and manganese to a subject in need of the treatment.
Dependencies are inferred from the claim text.