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US 12,734,146 B2Granted
Cobalt-porphyrin complexes for the inactivation of the biological activity of opioids
AssigneeThe Government of the United States of America, as represented by the Secretary of the Navy
InventorsOkhil Nag, D. Andrew Knight, James B. Delehanty
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Abstract
A cobalt-loaded porphyrin complex, comprising the porphyrin (meso-tri(4-sulfonatophenyl) mono(4-carboxyphenyl)porphine (C1S3TPP)) with coordinated with cobalt, effectively neutralizes the biological activity of opioids.
Claims4
A material comprising the porphyrin (meso-tri(4-sulfonatophenyl) mono(4-carboxyphenyl)porphine (C1S3TPP)) coordinated with cobalt, wherein the porphyrin has the following structure:
A medicament comprising:
- the porphyrin (meso-tri(4-sulfonatophenyl) mono(4-carboxyphenyl)porphine (C1S3TPP)) coordinated with cobalt, wherein the porphyrin has the following structure:
- and
- a pharmaceutically-acceptable carrier.
Dependencies are inferred from the claim text.