Back to results
US 12,733,948 B2Granted
Systems, methods and devices for progressively softening multi-compositional intravascular tissue
AssigneeCardiovascular Systems, Inc.
InventorVictor L. Schoenle
Life of this patent
Estimating the term…
Abstract
Various embodiments of the systems, methods and devices are provided comprising angioplasty to break up calcification or other tissue in occlusive areas within a blood vessel. The various embodiments disclosed comprise pressure pulse periods designed to break up calcified occlusive material through a cyclically stretching of the vessel walls without damaging the vessel wall tissue.
Claims21
A system for treating a blood vessel, including a blood vessel with a calcified lesion, the system comprising:
- a balloon operatively connected to a catheter,
- a fluid reservoir in operative fluid communication with the balloon, the balloon being inflatable within the blood vessel from a fluid within the fluid reservoir to a first pressure magnitude and to a first radial balloon diameter;
- a controller comprising a processor including memory and programmed instruction for delivering pressure pulses to fluid within the balloon for application to the calcified lesion of the blood vessel, the pressure pulses controlled to be delivered according to a pressure waveform and within at least one pressure pulse period, the pressure waveform of the at least one pressure pulse period including the pressure pulses with each pressure pulse having a pressure magnitude period and a pressure reduction period defined by and between successive pressure magnitudes, the pressure pulses and the pressure magnitudes configured to break up calcification, and the pressure magnitude period being 200 milliseconds or less with the pressure reduction period following a pressure magnitude period of 200 milliseconds or less being greater than the pressure magnitude period.
A system for treating a blood vessel, including a blood vessel with a calcified lesion, the system comprising:
- a balloon operatively connected to a catheter,
- a fluid reservoir in operative communication with the balloon, the balloon being inflatable within the blood vessel from a fluid within the fluid reservoir to a first pressure magnitude and to a first radial balloon diameter;
- a controller adapted to deliver a series of pressure pulses to fluid within the balloon with each pressure pulse having a pressure magnitude to be transferred by the balloon and for application to the calcified lesion of the blood vessel, the controller operatively connected with a microprocessor and memory with programmed instructions for creating a series of first pressure pulses according to a pressure waveform comprising a series of pressure magnitudes separated from one another by pressure reduction periods defined by and between the series of successive pressure magnitudes and transferring the pressure pulses from the balloon to the target blood vessel for applying higher pressure than the first pressure magnitude by each first pressure pulse to the target blood vessel and configured to break up calcification of the calcified lesion, the programmed instructions also used for reducing the pressure applied by the balloon to the target blood vessel for a first decompression period after the first pressure pulses that is longer than any pressure reduction period of the pressure pulses.
A system for treating a blood vessel, including a blood vessel with a calcified lesion, the system comprising:
- a balloon operatively connected to a catheter,
- a fluid reservoir in operative fluid communication with the balloon, the balloon being inflatable within the blood vessel from a fluid within the fluid reservoir to a first pressure magnitude and to a first radial balloon diameter;
- a controller comprising a processor including memory and programmed instruction for generating pressure pulses within the balloon for applying the pressure pulses to the calcified lesion of the blood vessel, the pressure pulses controlled to be delivered according to a pressure waveform and within at least one pressure pulse period, the pressure waveform of the at least one pressure pulse period including the pressure pulses with a similar pressure magnitude and a constant waveform period over the pressure pulse period, the pressure magnitudes being achieved within a pressure magnitude period of 200 milliseconds with a pressure reduction period defined by and between successive pressure magnitudes following the pressure magnitude period of 200 milliseconds or less being greater than the pressure magnitude period, and for creating a decompression period after the pressure pulse period.
Dependencies are inferred from the claim text.