Physiological measurement calibration
AssigneeMasimo Corporation
InventorsPrashanth Iyengar, Jerome Novak, Prashanth Rengaswamy Chandran
Life of this patent
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Abstract
The present disclosure provides a calibration system and method for calibrating a physiological measurement based on a variable that affects the measurement. The variable can be a related physiological measurement. The technique can be implemented to obtain robust calibrations with minimal test data and computational effort.
Claims19
A physiological monitoring system comprising:
- a sensor including a plurality of light emitters configured to shine light of known wavelengths into tissue of a patient and at least two detectors configured to detect the light after the light has been attenuated by the tissue, wherein an individual detector is provided for each different wavelength emitted by the plurality of light emitters;
- and
- a processor in communication with the sensor, the processor configured to receive the detected light and determine a non-invasive total hemoglobin measurement (SpHb) based on calibration information which decorrelates SpHb measurements from changes in a perfusion index of the patient.
A method for physiological parameter measurement calibration, the method comprising:
- shining light of a plurality of wavelengths into a patient's tissue;
- detecting the light after the light has been attenuated by the patient's tissue;
- obtaining a first measurement of the patient's SpHb and a related physiological parameter, wherein the first measurement is based at least in part on one or more attenuation ratios of absorption energies associated with each known wavelength of the light;
- obtaining a second measurement of the patient's SpHb and the related physiological parameter, wherein the patient's SpHb measurement is substantially the same and wherein the related physiological parameter is manipulated and the patient's SpHb is held the same;
- combining the first measurement and the second measurement with similar measurements from other patients to determine calibration information useful for decorrelating SpHb measurements from related physiological parameters;
- and
- based on the calibration information, configuring a physiological parameter measurement system to obtain a decorrelated SpHb measurement.
Non-transitory computer storage having stored thereon a system configured to execute in one or more processors, the system comprising a calibration module configured to:
- obtain a plurality of correlated measurements, each correlated measurement comprising a measurement of a selected physiological parameter and a measurement of a related physiological parameter;
- based on the plurality of correlated measurements, decorrelate the selected physiological parameter and the related physiological parameter;
- and
- based on the decorrelation of the selected physiological parameter and the related physiological parameter, determine calibration information;
- wherein the calibration information facilitates obtaining a decorrelated measurement of the selected physiological parameter;
- wherein the calibration module is further configured to use the calibration information to calibrate a physiological parameter measurement system to obtain the decorrelated measurement of the selected physiological parameter;
- wherein the physiological parameter measurement system includes a sensor having a plurality of light emitters configured to shine light of known wavelengths into tissue of a patient and at least two detectors configured to detect the light after attenuation by the tissue, wherein an individual detector is provided for each different wavelength emitted by the plurality of light emitters.
Dependencies are inferred from the claim text.