Implantable cerebral sensing devices and systems and methods related thereto

An implantable cerebral sensor comprising:

• a first insulator layer comprising a first polymer;
• a first electrode disposed on the first insulator layer and comprising a first conductor;
• a dielectric layer disposed on the first electrode and comprising a second polymer;
• a second electrode disposed on the dielectric layer and comprising a second conductor;
• and
• an outer shell substantially encasing the first insulator layer, the first electrode, the dielectric layer, and the second electrode;
• wherein:
• the second electrode is electrically separated from the first electrode by the dielectric layer;
• the first electrode and the second electrode each:
• have a thickness from 1 μm to 10 μm;
• and
• have a Young's modulus from 1 GPa to 100 GPa;
• the dielectric layer has a thickness from 1 μm to 10 μm;
• the first polymer and the second polymer each comprise a polyimide;
• the first conductor and the second conductor each comprise metal nanoparticles;
• the outer shell comprises an elastomer;
• the implantable cerebral sensor:
• is a passive sensor;
• has an original length;
• is deformably elastic when being stretched from 250% to 1000% of the original length;
• and
• has an electrical resistance that changes by less than or equal to 1Ω when being stretched from 250% to 1000% of the original length;
• the implantable cerebral sensor has a capacitance from 50 pF to 100 pF between the first electrode and the second electrode;
• the implantable cerebral sensor is conformally integrated with a stent configured to be implanted within a blood vessel;
• and
• the implantable cerebral sensor is configured to:
• deflect in response to intra-aneurysmal hemodynamics;
• sense, based on the deflection at a neck of an aneurysm, a condition in a blood vessel;
• and
• generate a wireless signal indicative of the sensed condition.

An implantable cerebral sensor system comprising:

• a stent configured to be implanted within a blood vessel;
• and
• an implantable cerebral sensor conformally integrated with the stent, the implantable cerebral sensor comprising:
• an insulator layer comprising a polyimide;
• a first electrode disposed on the insulator layer and comprising metal nanoparticles;
• a dielectric layer disposed on the first electrode and comprising a polyimide;
• a second electrode disposed on the dielectric layer and comprising metal nanoparticles, wherein the second electrode is electrically separated from the first electrode by the dielectric layer;
• and
• an outer shell substantially encasing the insulator layer, the first electrode, the dielectric layer, and the second electrode, wherein the outer shell comprises an elastomer;
• wherein:
• the implantable cerebral sensor is a passive sensor;
• the first electrode and the second electrode each have a thickness from 1 μm to 10 μm;
• the dielectric layer has a thickness from 1 μm to 10 μm;
• the implantable cerebral sensor has an unstretched length, is deformably elastic when being stretched from 250% to 1000% of the unstretched length, and has an electrical resistance that changes by less than or equal to 1Ω when being stretched from 250% to 1000% of the unstretched length;
• the implantable cerebral sensor has a capacitance from 50 pF to 100 pF between the first electrode and the second electrode;
• and
• the implantable cerebral sensor is configured to:
• deflect based on a fluid flow in a blood vessel;
• sense, based on the deflection, a condition in the blood vessel;
• and
• generate a wireless signal indicative of the sensed condition.