Biopsy cap for use with endoscope

A biopsy cap configured to be secured to a port of a medical device, the biopsy cap comprising:

• an outer shell having a proximal end, a distal end, and an interior volume defined within the outer shell between the proximal end and the distal end;
• two or more differently configured sections within said outer shell and arranged axially with respect to one another and each configured to contact an elongate member extended therethrough to at least partially reduce or prevent fluid flow through the biopsy cap;
• and
• a base member coupled to the distal end of the shell, distal to the interior volume, wherein the base member is configured to engage the port of the medical device to secure the biopsy cap with respect to the medical device;
• wherein at least one of the two or more differently configured sections comprises a plurality of radially inwardly extending members arranged in a helix;
• and
• wherein a space between adjacent members of the plurality of radially inwardly extending members tapers in a radially inward direction;
• and
• wherein a free end of each radially inwardly extending member meets other free ends at the center of the section.