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US 12,733,635 B2Granted
Platelet storage methods and compositions
AssigneePlatefuse, Inc.
InventorsYi Zheng, Jose Cancelas
Life of this patent
Estimating the term…
Abstract
Disclosed are compounds according to formula I: and compositions for slowing, preventing, or reversing platelet damage, particularly as may occur during blood banking or during refrigeration of platelets. Also disclosed herein are methods for storing platelets and methods of improving platelet survival upon transfusion with one or more compounds or compositions as described herein.
Claims8
A compound of Formula (I):
- or a pharmaceutically acceptable salt thereof, wherein:
- X1 is selected from a 3,4-dichlorophenyl, a 4-methylphenyl, or an unsubstituted 2-indole;
- X2 is selected from the group consisting of hydrogen, deuterium, halogen, and optionally substituted alkyl;
- and
- X3 is hydrogen, deuterium or an optionally substituted alkyl.
2 more elements
Dependencies are inferred from the claim text.