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US 12,731,258 B2Granted
Systems and methods for image processing to identify patients with pulmonary embolism
AssigneeWilliam Beaumont Hospital
InventorsEdward Castillo, Girish B. Nair
Life of this patent
Estimating the term…
Abstract
A method for processing images of lungs including defining lung segmentation of the lungs, performing deformable image registration on the segmented lungs, performing ventilation estimation operations to determine a ventilation estimation, performing perfusion estimation operations to determine a perfusion estimation, comparing the ventilation estimation to the perfusion estimation, and determining a pulmonary embolism risk score based on the comparison of the ventilation estimation to the perfusion estimation.
Claims20
A method for processing images of lungs, the method comprising:
- defining, via data processing hardware, lung segmentation of the lungs;
- performing, via the data processing hardware, deformable image registration on the segmented lungs;
- performing, via the data processing hardware, ventilation estimation operations to determine a ventilation estimation;
- performing, via the data processing hardware, perfusion estimation operations to determine a perfusion estimation;
- comparing, via the data processing hardware, the ventilation estimation to the perfusion estimation;
- determining, via the data processing hardware, a pulmonary embolism risk score based on the comparison of the ventilation estimation to the perfusion estimation;
- and
- wherein the pulmonary embolism risk score is determined by:
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31 more elements
A method for processing images of lungs, the method comprising:
- defining, via data processing hardware, lung segmentation of the lungs;
- performing, via the data processing hardware, deformable image registration on the segmented lungs;
- performing, via the data processing hardware, ventilation estimation operations to determine a ventilation estimation;
- performing, via the data processing hardware, perfusion estimation operations to determine a perfusion estimation;
- comparing, via the data processing hardware, the ventilation estimation to the perfusion estimation;
- determining, via the data processing hardware, a pulmonary embolism risk score based on the comparison of the ventilation estimation to the perfusion estimation;
- wherein the lungs are segmented into five regions;
- wherein the pulmonary embolism risk score is on a scale from 0 to 5 based on the number of lung regions that have ventilation/perfusion mismatch;
- and
- wherein ventilation/perfusion mismatch is defined by:
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136 more elements
A method for processing images of lungs, the method comprising:
- defining, via data processing hardware, lung segmentation of the lungs;
- performing, via the data processing hardware, deformable image registration on the segmented lungs;
- performing, via the data processing hardware, ventilation estimation operations to determine a ventilation estimation;
- performing, via the data processing hardware, perfusion estimation operations to determine a perfusion estimation;
- comparing, via the data processing hardware, the ventilation estimation to the perfusion estimation;
- determining, via the data processing hardware, a pulmonary embolism risk score based on the comparison of the ventilation estimation to the perfusion estimation;
- and
- wherein optimal threshold values are determined by:
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71 more elements
A system comprising:
- data processing hardware;
- and
- memory hardware in communication with the data processing hardware, the memory hardware storing instructions that when executed on the data processing hardware cause the data processing hardware to perform operations comprising:
- defining lung segmentation of the lungs;
- performing deformable image registration on the segmented lungs;
- performing ventilation estimation operations to determine a ventilation estimation;
- performing perfusion estimation operations to determine a perfusion estimation;
- comparing the ventilation estimation to the perfusion estimation;
- determining a pulmonary embolism risk score based on the comparison of the ventilation estimation to the perfusion estimation;
- and
- wherein the pulmonary embolism risk score is determined by:
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34 more elements
Dependencies are inferred from the claim text.