Bacillus cell with reduced lipase and/or esterase side activities
AssigneeBASF SE
InventorsStefan Jenewein, Max Fabian Felle, Christopher Sauer, Paul Igor Costea
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Abstract
The present invention provides a modified Bacillus cell for the production of a compound of interest, wherein the Bacillus cell comprises a genetic modification that leads to decreased production of enzymes with lipase and/or esterase activity. The use of compounds of interest produced with said improved Bacillus host cells reduces the formation of malodour and/or off-flavour when used for applications such as washing or cleaning or as feed or food additives.
Claims13
A recombinant Bacillus cell comprising inactivated yitV and ypmR genes, wherein the recombinant Bacillus cell does not produce active YitV protein and does not produce active YpmR protein.
A method for reducing the lipase and/or esterase activity in a Bacillus cell comprising inactivating the yitV and/or ypmR gene in the Bacillus cell.
Dependencies are inferred from the claim text.