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A compound of formula (II), or a salt, solvate, stereoisomer, tautomer, isotopically labelled derivative, or geometric isomer thereof:

• wherein:
• R20 is selected from the group consisting of
• and C5 heteroaryl optionally substituted with C1-C6 alkyl;
• R21 is selected from the group consisting of H, D, and C1-C12 alkyl;
• R22 is selected from the group consisting of unsubstituted C6-C12 aryl, unsubstituted C4-C10 heteroaryl, and phenyl substituted with one or more substituents selected from the group consisting of CF3, CCl3, CBr3, Cl3, C1-C6 alkyl, and C1-C6 haloalkoxy;
• R23 is selected from the group consisting of (CH2)mC(═O)NHR24, (CH2)nC(═O)OH, (CH2)pC(═O)OR24, C3-C7 cycloalkyl, and C3-C7 heterocyclyl, wherein the C3-C7cycloalkyl and the C3-C7 heterocyclyl are each optionally substituted with C(═O)NHR25;
• R24 and R25 are each independently a-C1-C6 alkyl;
• m, n, and p are each independently 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10;
• wherein, when R20 is an unsubstituted Cs heteroaryl, R23 is (CH2)nC(═O)NHR24;
• and
• wherein, when R22 is unsubstituted C6 aryl, R21 is methyl.