Controlled-release progesterone compositions and uses thereof
AssigneeCeva Sante Animale
InventorsFlorence Guimberteau, Sandrine Lacoste
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Abstract
The present invention relates to a composition comprising between 35 and 55% by weight of a polymer matrix comprising a thermoplastic polymer having a Shore A hardness of between 20 and 100 as measured by a Type A durometer according to the ASTM D2240 standard and a melting point of between 40 and 200° C.; and between 30 and 55% by weight of progesterone relative to the total weight of the composition. The invention further relates to the use of such compositions to synchronise the estrus of a group of non-human mammals, preferably a group of bovines.
Claims20
A composition comprising:
- between 35 and 55% by weight of a polymer matrix comprising a thermoplastic polymer having a Shore A hardness of between 20 and 100 as measured by a Type A durometer according to the ASTM D2240 standard and a melting point of between 40 and 200° C.;
- and
- between 30 and 55% by weight of progesterone,
- relative to the total weight of the composition.
A composition comprising:
- a polymer matrix comprising a thermoplastic polymer having a Shore A hardness of between 20 and 100 as measured by a Type A durometer according to the ASTM D2240 standard and a melting point of between 4° and 200° C.;
- and
- progesterone,
- wherein the ratio by weight of progesterone to the polymer matrix is between 0.5 and 2.
A composition comprising:
- a polymer matrix comprising a thermoplastic polymer having a Shore A hardness of between 20 and 100 as measured by a Type A durometer according to the ASTM D2240 standard and a melting point of between 40 and 200° C.;
- and
- progesterone,
- wherein the area density of progesterone in the polymer matrix is between 20 and 100 mg/cm2.
Dependencies are inferred from the claim text.