Compositions and methods for monitoring, diagnosis, detection and treatment of cancer
AssigneeGLAX Health LLC
InventorsShivani Shrivastava, Rakesh K. Srivastava
Life of this patent
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Abstract
The present invention relates to the use of compositions for monitoring, diagnosis, detecting, and treating a cancer condition in a subject. The use of composition comprises methods of monitoring, diagnosis, and detecting cancer and inflammation with EN2 and/or SATB2 expression and/or activity. The pharmaceutical composition will further comprise agents that inhibit EN2 and/or SATB2 expression or activity.
Claims14
A method for treating cancer in a subject, comprising administering to the subject a pharmaceutical composition comprising an effective amount of at least one agent that inhibits at least one of EN2 expression or EN2 transcriptional activity, and at least one of SATB2 expression or SATB2 transcriptional activity, wherein
- SATB2 and EN2 are expressed in the cancer,
- the cancer is selected from the group consisting of human breast cancer, prostate cancer, colorectal cancer, pancreatic cancer, gastric cancer, liver cancer, lung cancer, cancer stem cells, mesothelioma, brain cancer, ovarian cancer, head and neck cancer, sarcoma, kidney cancer, melanoma, multiple myeloma, leukemia, and lymphoma, and
- the at least one agent is one of the following chemical structures:
Dependencies are inferred from the claim text.