Methods of treating inflammation

A method of treating inflammation in a subject in need thereof by administering to the subject a formulation having a therapeutically effective amount of a compound of Formula (I):

• wherein
• A is phenyl, indolyl, or indazolyl, optionally substituted with at least one of (C1-C4)alkyl, halo(C1-C4)alkyl, O—(C1-C4)alkyl, O—(C1-C4)haloalkyl, (C1-C4)alkylamino, amino(C1-C4)alkyl, F, Cl, Br, I, CN, —CH2CN, NH2, hydroxyl, OC(O)CF3, —OCH2Ph, —NHCO—(C1-C4)alkyl, COOH, —C(O)Ph, C(O)O—(C1-C4)alkyl, C(O)H, —C(O)NH2 or NO2;
• B is an imidazole or benzimidazole, optionally substituted with at least one of (C1-C4)alkyl, halo(C1-C4)alkyl, O—(C1-C4)alkyl, O-halo(C1-C4)alkyl, F, Cl, Br, I, CN, —CH2CN, hydroxyl, or NO2;
• R1, R2 and R3 are independently at least one of hydrogen, (C1-C4)alkyl, halo(C1-C4)alkyl, O—(C1-C4)alkyl, O—(C1-C4)haloalkyl, (C1-C4)alkylamino, amino(C1-C4)alkyl, F, Cl, Br, I, CN, —CH2CN, NH2, hydroxyl, OC(O)CF3, —OCH2Ph, —NHCO—(C1-C4)alkyl, COOH, —C(O)Ph, C(O)O—(C1-C4)alkyl, C(O)H, —C(O)NH2 or NO2;
• X is a bond or NH;
• Y is a bond or —C═O;
• and
• m is 1-3, or a pharmaceutically acceptable salt, hydrate, or stereoisomer thereof wherein the inflammation is caused by or associated with SARS-CoV, MERS-CoV, or SARS-CoV-2.