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US 12,728,103 B2Granted
Pharmaceutical composition comprising mitotane administered orally for treatment of adrenocortical carcinoma and Cushing's syndrome
OwnerMohamed Skiba, Malika Lahiani-Skiba +3inventors
InventorsMohamed Skiba, Malika Lahiani-Skiba, Frédéric Bounoure, Michael Thomas, Hervé Lefebvre
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Abstract
An object of the present invention is the preparation and use of a new dry emulsion (DE) containing mitotane and its use for the oral route for the treatment of adrenocortical carcinoma, congenital adrenal hyperplasia and Cushing's syndrome.
Claims12
A formulation of mitotane dry emulsion comprising:
- an oily phase enriched with mitotane and cyclodextrin containing, or not, a co-solvent and/or an absorption promoter.
Dependencies are inferred from the claim text.