Cryogenic device and actuator assembly therein

Kit for assembling a device for the topical cryotherapy of dermatological disorders, such as warts, in a subject in need thereof, the kit comprising:

• a housing for holding a pressurized carbon dioxide cartridge, said housing defining a cavity sized to receive and support said cartridge;
• a pressurized carbon dioxide cartridge;
• an applicator nozzle comprising (i) an internal channel disposed in the housing for guiding the outflow of carbon dioxide from said pressurized carbon dioxide cartridge, and (ii) an applicator surface formed at an end of the housing preferably comprising an adhesion surface ring onto which a carbon dioxide ice tablet may be formed, wherein the applicator surface defines an outlet of the internal channel;
• an actuator mechanism for controlling an outflow of carbon dioxide from said pressurized carbon dioxide cartridge to said applicator nozzle, which actuator mechanism is movable between a first, closed position and between a second, open position;
• and further comprising
• a closing cap, detachably provided across from said applicator surface, said closing cap comprising a cup which, in an arranged position, faces towards said applicator surface, thereby forming a sublimation chamber between said cup of said closing cap and said applicator surface;
• whereby said cup, in said arranged position, is configured to prevent the outflow of carbon dioxide gas from said sublimation chamber so that solid carbon dioxide ice forms in the sublimation chamber and is attached to and covers the applicator surface;
• said applicator nozzle defining a venting hole upstream of said applicator surface, said venting hole in fluid communication with said internal channel, said cup further defining a venting cavity, and whereby said venting hole and said venting cavity, in said arranged position, are aligned to permit evacuation of carbon dioxide from said internal channel and pressure to drop in said sublimation chamber.