Automated seizure detection, quantification, warning and therapy delivery using the slope of heart rate
OwnerIvan Osorioinventor
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Abstract
A system and method for detecting seizures in a patient are disclosed. The method includes measuring at least one signal associated with the patient over a first time period, and calculating a first slope having a rate of change in a first signal of the at least one signal over the first time period. The first signal is a heart rate. The method also includes determining a difference between the first slope and a reference slope, as well as detecting an epileptic seizure based at least upon the difference between the first slope and the reference slope. Furthermore, the method includes quantifying the epileptic seizure by calculating a severity of the seizure. The severity is the product of a seizure duration and a seizure intensity.
Claims20
A medical device for detecting seizures in a patient, comprising:
- a cardiac sensor configured to measure a heart rate of the patient over at least a first time period equivalent to three heart beats of the patient;
- a controller communicatively coupled to the cardiac sensor and configured to:
- receive the heart rate from the cardiac sensor;
- calculate a first slope, the first slope being at least an estimate of a rate of change in the heart rate over the first time period;
- determine a difference between the first slope and a reference slope, the reference slope being a reference value for changes in R-R interval durations during non-ictal conditions;
- detect an epileptic seizure based upon the difference between the first slope and the reference slope;
- and
- automatically deliver a warning and a treatment to the patient in response to the detection of an epileptic seizure, the treatment being one of an electrical stimulation and a seizure drug treatment;
- wherein the first slope is calculated by comparing a time interval between a first R wave peak and a second R wave peak with a time interval between the second R wave peak and a third R wave peak.
A method for detecting seizures in a patient, comprising:
- receiving at a controller, a heart rate of the patient measured by a cardiac sensor over at least a first time period equivalent to three heart beats of the patient,
- calculating a first slope with the controller, the first slope being at least an estimate of a rate of change in the heart rate over the first time period;
- determining, with the controller, a difference between the first slope and a reference slope, the reference slope being a reference value for changes in R-R interval durations during non-ictal conditions;
- detecting, with the controller, an epileptic seizure based upon the difference between the first slope and the reference slope;
- and
- automatically delivering a warning and a treatment to the patient in response to detecting the epileptic seizure, the treatment being one of an electrical stimulation and a seizure drug treatment;
- wherein the first slope is calculated by comparing a time interval between a first R wave peak and a second R wave peak with a time interval between the second R wave peak and a third R wave peak.
Dependencies are inferred from the claim text.