Method and apparatus for analyzing pathological slide images

A computing apparatus comprising:

• a memory storing at least one program;
• and
• a processor configured to perform at least one operation by executing the at least one program,
• wherein the processor is further configured to:
• analyze a pathological slide image to classify at least one of cells and tissues included in the pathological slide image into at least one type;
• segment the pathological slide image into subpatches based on a result of the classification;
• analyze the subpatches to output information regarding components of a cell included in each of the subpatches;
• generate, by using a machine learning model, subcell information including a first index and a second index for at least one of the components determined based on information regarding the subpatches and the components;
• calculate a third index corresponding to a cell membrane specificity of the at least one of cells and tissues included in the pathological slide image based on the second index, wherein the cell membrane specificity indicates how much of a targeted object is present in a cell membrane of the cell;
• control a display apparatus to display information regarding the third index of the at least one of cells and tissues;
• control the display apparatus to display at least one of a visualization result of the second index for at least one of components of each of cells included in the pathological slide image and a visualization result of the first index for any one of the components;
• control the display apparatus to display a graph indicating a distribution of scores corresponding to a staining intensity of at least one of a membrane, cytoplasm, and a cell nucleus of each of the cells included in the pathological slide image;
• and
• control the display apparatus to replace a heatmap generated based on a score corresponding to the second index with visualization results of components of each of the cells and display the visualization result, based on an enlargement magnification set according to a user input being a preset magnification or more,
• wherein the visualization results of the components of each of the cells comprise at least one of a first visualization element in which an outline corresponding to a cell membrane of each of the cells is displayed in a certain color and a second visualization element in which a figure generated based on a class corresponding to the first index being displayed at a central point of each of the cells.