Method for three-dimensional replication of a biological tissue

A method for applying a substance (11) that is created through bringing together a first precursor and a second precursor, wherein the substance (11), once created, is capable of adhering cells, the method comprising the steps of:

• provision of a substrate (01);
• deposit of primary cells (08) of a cell type on the substrate (01);
• arrangement of the first precursor of the substance (11) adhering the cells (08, 13) on at least a selection of the primary cells (08) of the cell type;
• and arrangement in a locally targeted manner of the second precursor (12) of the substance (11) adhering the cells (08, 13) to the selection of primary cells (08) of the cell type according to a structure formed by cells of the cell type in a tissue to be reproduced, whereby the first precursor and the second precursor (12) react with each other to form the substance (11) adhering the cells (08, 13), which substance adheres the selection of primary cells (08) of the cell type according to the structure formed by the cells of the cell type in the tissue to be reproduced and forms a first layer of the primary cells (08) such that the selection of primary cells (08) of the cell type constitutes a reproduction of at least a first section of the biological tissue to be reproduced.