Antibody specifically binding to human serum albumin
AssigneeNumab Therapeutics AG
InventorsDavid Urech, Christian Hess, Alexandre Simonin, Stefan Warmuth
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Abstract
The present invention relates to a multispecific antibody comprising at least one domain specifically binding to a tumor-associated immune checkpoint antigen with low affinity, and at least one domain specifically binding to a tumor-associated antigen (TAA), and pharmaceutical compositions and methods of use thereof. The present invention further relates to a nucleic acid encoding said multispecific antibody, a vector comprising said nucleic acid, a host cell comprising said nucleic acid or said vector, and method of producing said multispecific antibody.
Claims15
An antibody or antigen-binding fragment thereof specifically binding to human serum albumin (HSA), that comprises HCDR1, HCDR2, and HCDR3 sequences of SEQ ID NOs:
- 61, 62 and 63, respectively, and LCDR1, LCDR2, and LCDR3 sequences of SEQ ID NOs:
- 64, 65 and 66, respectively.
Dependencies are inferred from the claim text.