Cinnamoyl amino acid compound and use thereof
AssigneeChina Pharmaceutical University
InventorsHao Wang, Xiaolong Hu, Xianyu Lv, Fei Xiong, Jiahao Feng
Life of this patent
Estimating the term…
Abstract
Cinnamoyl amino acid compounds and a use thereof, which relate to the fields of medicinal chemistry and pharmacotherapeutics, and specifically relate to cinnamoyl amino acid compounds having inducible nitric oxide synthase (iNOS) inhibitory activity or a pharmaceutically acceptable salt thereof, a pharmaceutical composition including the compounds, and a medical use thereof, particularly an application thereof in the prevention and treatment of neurodegenerative diseases related to nerve cell damage, including ischemic stroke, Parkinson's disease, and so on.
Claims2
A method of treating a neurodegenerative disease in a subject in need thereof wherein said method comprises administering a composition comprising:
- 4-trifluoromethyl-cinnamoyl-4-fluoro-L-phenylalanine, being shown in structural formula I or a pharmaceutically acceptable salt thereof drug:
- and
- the neurodegenerative disease is related to nerve cell damage and is ischemic stroke or Parkinson's disease.
Dependencies are inferred from the claim text.