Surface molecularly imprinted magnetic nanometer material of salvianolic acid A, preparation method therefor and use thereof

Abstract

Providing a surface molecularly imprinted magnetic nanomaterial of salvianolic acid A, a preparation method therefor and use thereof. The nanomaterial is obtained by using ferroferric oxide nanoparticles as a core, salvianolic acid A as a template molecule, 4-acryloyloxy phenylboronic acid, vinyl imidazole and methacryloylpropyl trimethyl ammonium chloride as copolymerization functional monomers, bismethylene acrylamide as a cross-linking agent, and azoamidine initiator V50 as an initiator, synthesizing surface imprinted magnetic material containing template molecules by surface polymerization, and finally eluting the template molecule with 0.1 M HCl. It is a spherical particle with a core-shell structure of about 250 nm, with positive charge on the surface and strong hydrophilicity, which can be recycled. Moreover, this magnetic material is easy to be separated by a magnet. The surface molecularly imprinted magnetic nanomaterial prepared by the present application can be used for rapid, large-capacity and high-selectivity separation and enrichment of salvianolic acid A.

Dependencies are inferred from the claim text.