# US 12,722,011 B2 · Algorithm for adjusting a compliance voltage in a stimulator device having neural sensing capability > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,722,011 B2 - Document ID: US12722011B2 - Status: Granted - Kind: B2 - Application number: 18/152,636 - Filed: 2023-01-10 - Published: 2023-08-10 - Granted: 2026-09-01 - Earliest claimed: 2022-01-14 - Assignees: Boston Scientific Neuromodulation Corporation - Applicants: Boston Scientific Neuromodulation Corporation - Inventors: Pujitha Weerakoon; Goran N. Marnfeldt - Web page: https://patentgrep.com/patent/US12722011B2 ## CPC - A61N 1/36125: {Details of circuitry or electric components} - A61N 1/36139: {with automatic adjustment} - A61N 1/36135: {using physiological parameters} - A61N 1/36153: {Voltage (A61N1/3616 takes precedence)} - A61N 1/36157: {Current (A61N1/3616 takes precedence)} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract An optimization algorithm is disclosed for optimizing an implantable pulse generator. The algorithm is particularly useful when one or more of the electrodes (e.g., the case electrode) is used to provide a common mode voltage (Vcm) to the tissue, which assists in sensing neural responses to the stimulation. The algorithm preferably optimizes both the compliance voltage VH used to power the simulation circuitry, and the strength of tissue driver circuitry used to provide Vcm to the tissue. The algorithm preferably considers information determined by VH measurement circuitry (which informs as to the ability to form prescribed stimulation pulses without loading), sensing monitoring circuitry (which informs as to the magnitude of the inputs of the sensing circuitry), and/or tissue monitoring circuitry (which informs as to adequacy of the strength of the tissue driver circuitry). ## Claims ### Claim 1 A method for operating a stimulator device having a plurality of electrodes comprising at least one sensing electrode, at least two stimulation electrodes, and at least one common mode electrode, the method comprising: receiving signals from a patient's tissue at the at least one sensing electrode, and providing the received signal to at least one input of a sense amp circuit; providing a common mode voltage to the tissue at the at least one common mode electrode, wherein a tissue current at the common mode electrode is limited to a programmable first magnitude; executing a stimulation program to provide a stimulation current of a prescribed amplitude between the at least two stimulation electrodes and through the patient's tissue using stimulation circuitry powered by a compliance voltage; generating at least one first control signal indicating whether the tissue current has reached the first magnitude; generating at least one second control signal indicating whether a second magnitude at the at least one input is appropriate for sensing the signals from the patient's tissue; generating at least one third control signal indicating whether the stimulation current is provided by the stimulation circuitry at the prescribed amplitude without loading; and executing an algorithm in the stimulator device, wherein the algorithm is configured to use the at least one first control signal, the at least one second control signal, and the at least one third control signal to adjust the compliance voltage. ### Claim 2 (depends on 1) The method of claim 1, wherein the algorithm is configured to adjust the compliance voltage to a lowest value at which the stimulation current is provided by the stimulation circuitry at the prescribed amplitude without loading; and either or both of the following occurs: the tissue current has not reached the first magnitude, or the second magnitude at the at least one input is appropriate for sensing the signals from the patient's tissue. ### Claim 3 (depends on 2) The method of claim 2, wherein the algorithm is configured to initially set the compliance voltage to a maximum voltage. ### Claim 4 (depends on 1) The method of claim 1, wherein the algorithm is further configured to use either or both of the at least one first control signal and the at least one second control signal to adjust the first magnitude. ### Claim 5 (depends on 4) The method of claim 4, wherein the algorithm is configured to adjust the first magnitude to a lowest value at which either or both of the following occurs: the tissue current has not reached the first magnitude, or the second magnitude at the at least one input is appropriate for sensing the signals from the patient's tissue. ### Claim 6 (depends on 4) The method of claim 4, wherein the algorithm is configured to adjust the compliance voltage before adjusting the first magnitude. ### Claim 7 (depends on 4) The method of claim 4, wherein the algorithm is configured to adjust the first magnitude using the at least one first control signal. ### Claim 8 (depends on 4) The method of claim 4, wherein the algorithm is configured to adjust the first magnitude using the at least one second control signal. ### Claim 9 (depends on 4) The method of claim 4, wherein the algorithm is configured to adjust the first magnitude using the at least one first control signal and the at least one second control signal. ### Claim 10 (depends on 4) The method of claim 4, wherein the algorithm is configured to initially set the first magnitude to a maximum value. ### Claim 11 (depends on 10) The method of claim 10, wherein the algorithm is configured to use either or both of the at least one first control signal and the at least one second control signal to reduce the first magnitude to a lowest value. ### Claim 12 (depends on 1) The method of claim 1, wherein the algorithm is further configured to select at least one of the electrodes as the at least one sensing electrode. ### Claim 13 (depends on 12) The method of claim 12, wherein the algorithm is further configured to select at least one of the electrodes as the at least one sensing electrode prior to adjusting the compliance voltage. ### Claim 14 (depends on 13) The method of claim 13, wherein the algorithm selects the at least one sensing electrode upon determining that either or both of the following occurs: the tissue current has not reached the first magnitude, or the second magnitude at the at least one input is appropriate for sensing the signals from the patient's tissue. ### Claim 15 (depends on 1) The method of claim 1, wherein the algorithm is further configured to modify or suggest a modification to the stimulation program. ### Claim 16 (depends on 15) The method of claim 15, wherein the algorithm is configured to continue modifying or suggesting the modification to the stimulation program until determining that either or both of the following occurs: the tissue current has not reached the first magnitude, or the second magnitude at the at least one input is appropriate for sensing the signals from the patient's tissue. ### Claim 17 A stimulator device having a plurality of electrodes comprising at least one sensing electrode, at least two stimulation electrodes, and at least one common mode electrode, the device comprising: a sense amp circuit configured to receive at at least one input signals from a patient's tissue at the at least one sensing electrode; tissue driver circuitry configured to provide a common mode voltage to the tissue at the at least one common mode electrode, wherein a tissue current at the common mode electrode is limited to a programmable first magnitude; stimulation circuitry configured to execute a stimulation program to provide a stimulation current of a prescribed amplitude between the at least two stimulation electrodes and through the patient's tissue, wherein the stimulation circuitry is powered by a compliance voltage; first measurement circuitry configured to generate at least one first control signal indicating whether the tissue current has reached the first magnitude; second measurement circuitry configured to generate at least one second control signal indicating whether a second magnitude at the at least one input is appropriate for sensing the signals from the patient's tissue; third measurement circuitry configured to generate at least one third control signal indicating whether the stimulation current is provided by the stimulation circuitry at the prescribed amplitude without loading; and control circuitry programmed with an algorithm, wherein the algorithm is configured to use the at least one first control signal, the at least one second control signal, and the at least one third control signal to adjust the compliance voltage.