Antiviral agent for combined therapy of COVID-19 (SARS-CoV-2)

Abstract

This invention relates to a novel anti-coronavirus agent for COVID-19 (SARS-CoV-2) combination therapy. The agent comprises, in a therapeutically effective amount and ratio, aprotinin (APR) or a medicinal drug based thereon and a SARS-CoV-2 replication inhibitor. The aprotinin-based medicinal drug is preferably selected from the group consisting of Aprotex, Vero-Narcap, Ingitril, Contrykal, Kontrisel, Trasilol®, Ingiprol, Aprotimbin, Gordox®, Contriven, Trascolan, or Aerus. For SARS-CoV-2 replication inhibitor one can use favipiravir (FPV) or Remdesivir (RMD), or a medicinal drug based thereon. The favipiravir-based medicinal drug is preferably selected from the group consisting of Avigan, Favilavir, Avifavir, Coronavir, or Fabiflu. Further, the invention relates to a combination method to treat COVID-19 (SARS-CoV-2) by administering said anti-coronavirus agent to a patient with COVID-19. The use of the novel anti-coronavirus agent in COVID-19 (SARS-CoV-2) therapy leads to a new, synergistic effect and allows one to significantly reduce the duration of treatment and mitigate the risk of undesirable side effects.

Dependencies are inferred from the claim text.