Extracellular vesicles from stem cells to treat and/or prevent disease
AssigneeChildren's Hospital Los Angeles
InventorsLaura Perin, Sargis Sedrakyan, Benedetta Bussolati, Roger De Filippo
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Abstract
Compositions and methods to treat or prevent disease or injury comprising administering an effective amount of extracellular vesicles (EVs) isolated from stem cells to a subject in need thereof.
Claims6
A method to ameliorate a symptom of treat Alport syndrome in a human subject comprising administering an effective amount of extracellular vesicles (EVs) isolated from human stem cells to a subject in need thereof, wherein the extracellular vesicles are administered intravenously or by local injection, wherein the stem cells are amniotic fluid stem cells (AFSCs).
Dependencies are inferred from the claim text.