Cinnamamide derivatives and use thereof

A pharmaceutical composition for treating cancer associated with signal transducers and activators of transcription 3 (STAT 3) activity, comprising a compound represented by Chemical Formula 1 below, or a pharmaceutically acceptable salt thereof, as an active ingredient:

• In Chemical Formula 1,
• R1 is C1-6 alkyl;
• hydroxy;
• halogen;
• C1-6 alkynyloxy;
• or unsubstituted or substituted C1-6 alkoxy;
• wherein the substituted C1-6 alkoxy contains C1-6 aryl or 5- to 14-membered heteroaryl as a substituent,
• wherein the heteroaryl contains one or more O, N, or S, and
• R2 is hydrogen or alkyl.

A method for treating cancer associated with signal transducers and activators of transcription 3 (STAT3) activity, comprising administering a pharmaceutical composition containing a compound represented by Chemical Formula 1 below, or a pharmaceutically acceptable salt thereof, as an active ingredient, into a subject:

• In Chemical Formula 1,
• R1 is C1-6 alkyl;
• hydroxy;
• halogen;
• C1-6 alkynyloxy;
• or unsubstituted or substituted C1-6 alkoxy;
• wherein the substituted C1-6 alkoxy contains C1-6 aryl or 5- to 14-membered heteroaryl as a substituent,
• wherein the heteroaryl contains one or more O, N, or S, and
• R2 is hydrogen or alkyl.