Injectable tissue repair devices and processes for preparation thereof
AssigneeDsm IP Assets B.V.
InventorsJulia Innamorato, Rachel Dichter, Nicholas Roscioli, Andrew Hall
Life of this patent
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Abstract
Disclosed are tissue repair devices, processes for preparing such devices, and methods of use of such devices. In an embodiment, a tissue repair device comprises porous, compressible pellets of a tissue repair material that may be provided and then hydrated in the barrel of a syringe. In an embodiment, the tissue repair material is configured in the barrel of the syringe such that an elongate channel is present, the channel being defined by the interior wall of the barrel and the tissue repair material.
Claims23
A method of forming a tissue repair device comprising the steps of:
- a. providing a syringe comprising a barrel that is configured or configurable to be in fluid communication with a tip, the barrel comprising an interior wall, a tissue repair material, and an elongate channel extending over a length of the barrel, the elongate channel being defined by the interior wall and the tissue repair material and the elongate channel being configured such that the tissue repair material does not contact the interior wall within the elongate channel along the length, wherein the tissue repair material comprises porous, compressible pellets and the tissue repair material is porous and compressed;
- and
- b. inserting a hydrating fluid into the elongate channel to form an extrudable tissue repair material.
A tissue repair device comprising:
- a syringe comprising a barrel in fluid communication with a tip, the barrel comprising an interior wall and a porous, compressed tissue repair material comprising porous, compressible pellets present in the barrel,
- wherein the tissue repair device comprises an elongate channel extending over a length of the barrel through the tissue repair material,
- wherein the elongate channel is defined by the interior wall and the tissue repair material, the elongate channel being configured such that the tissue repair material does not contact the interior wall within the elongate channel along the length, and
- wherein the tissue repair material comprises collagen fibers and mineral particles.
A method for forming a tissue repair device comprising the steps of:
- a. providing a syringe comprising a barrel that is configured or configurable to be in fluid communication with a tip, the barrel comprising an interior wall and at least one elongate obstruction extending over a length of the barrel, the at least one elongate obstruction being in contact with or proximate to the interior wall;
- b. inserting into the barrel a plurality of porous, compressible pellets of a tissue repair material, the tissue repair material being extrudable via the tip upon hydration;
- c. compressing at least some of the plurality of porous, compressible pellets;
- and
- d. removing the at least one elongate obstruction.
Dependencies are inferred from the claim text.