Method of and system for in vivo strain mapping of an aortic dissection

A system comprising:

• a processor;
• and
• a non-transitory storage medium operatively connected to the processor, the non-transitory storage medium comprising computer-readable instructions stored thereon;
• the processor, upon executing the computer-readable instructions, being configured for:
• receiving a multiphase stack having been generated from a plurality of images of the dissected blood vessel of the given subject, each one of phases of the multiphase stack being representative of the dissected blood vessel at a respective time in a cardiac cycle;
• generating, using at least a portion of the multiphase stack, a 3D geometrical model of at least a portion of the dissected blood vessel, the 3D geometrical model comprising a wall of the dissected blood vessel and a dissection flap;
• generating, using the 3D geometrical model, a surface mesh of at least the portion of the dissected blood vessel for a given one of the phases of the multiphase stack, the surface mesh of at least the portion of the dissected blood vessel comprising a blood vessel wall surface mesh and a dissection flap surface mesh;
• determining, using the surface mesh of at least the portion of the dissected blood vessel and the multiphase stack, a local deformation at each phase of the multiphase stack by mapping each node of the surface mesh of the dissected blood vessel to a respective voxel of each one of the phases of the multiphase stack;
• generating, using the local deformation at each one of the phases and the blood vessel wall surface mesh and the dissection flap surface mesh, a set of strain maps, a given strain map of the set of strain maps including principal strain values at the surface of the dissected blood vessel for a corresponding phase of the cardiac cycle;
• and
• outputting the set of strain maps.