Anti-viral paints and coatings and articles comprising same

A composition effective as a treatment on a surface of a substrate subject to contamination by a microbial contaminant that is communicable to humans to thereby provide the substrate with an anti-contaminant functionalized surface, the composition comprising:

• a surface treatment composition;
• and
• an anti-contaminant additive combined with the surface treatment composition, wherein the anti-contaminant additive and the surface treatment composition are combined in respective amounts effective in enabling the anti-contaminant functionalized surface to neutralize activity of at least a portion of a quantity of particles of the microbial contaminant after the quantity of particles of the microbial contaminant become deposited on the anti-contaminant functionalized surface, wherein the anti-contaminant additive comprises an enzyme effective to break ester linkages of lipids of a biological surrogate of the microbial contaminant and an antimicrobial peptide effective to disrupt microbial membranes of the biological surrogate, wherein the anti-contaminant additive comprising the enzyme and the antimicrobial peptide provide the anti-contaminant functionalized surface with increased neutralization of activity of the microbial contaminant as compared to said neutralization when the anti-contaminant additive comprises only the enzyme or the antimicrobial peptide, and wherein the biological surrogate comprises an enveloped bacterial virus characterized by having a lipid-containing viral membrane envelope.