Back to results
US 12,716,895 B2Granted
Low voltage reduced graphene oxide (rGO)-based biosensor
AssigneeKhalifa University of Science and Technology
InventorsShadi Wajih Hasan, Habiba Alsafar, Ahmed Fayez Yousef, Vijay Kumar Shankarayya Wadi, Lina Tizani, Dana Kadadou
Life of this patent
Estimating the term…
Abstract
In some embodiments, a method includes applying an analyte to a rGO biosensor configured to bind to the analyte; applying a DC voltage to the rGO biosensor, wherein the DC voltage is +0.0008 V to +0.005 V for a negatively charged analyte; or −0.005 V to −0.0008 for a positively charged analyte; and monitoring an electrical signal from the rGO biosensor for a response to the analyte.
Claims18
A method comprising:
- applying an analyte to a rGO biosensor configured to bind to the analyte;
- applying a DC voltage to the rGO biosensor while monitoring an electrical signal from the rGO biosensor, wherein the DC voltage is:
- +0.0008V to +0.005V for a negatively charged analyte;
- or
- −0.005V to −0.0008V for a positively charged analyte;
- and
- detecting a response to the analyte based on a change in the monitored electrical signal.
4 more elements
A method of detecting an analyte using a reduced graphene oxide (rGO) biosensor, comprising:
- applying the analyte to the rGO biosensor functionalized with a bioreceptor configured to bind the analyte;
- applying a DC voltage across the rGO biosensor, wherein the DC voltage is:
- +0.0008V to +0.005V for a negatively charged analyte;
- or
- −0.005V to −0.0008V for a positively charged analyte;
- measuring an electrical current through the rGO biosensor over time while the DC voltage is applied;
- determining an initial baseline current prior to binding of the analyte to the rGO biosensor;
- calculating a normalized current signal based on the measured electrical current relative to the initial baseline current;
- and
- detecting the analyte by identifying a peak in the normalized current signal indicative of binding of the analyte to the rGO biosensor.
7 more elements
Dependencies are inferred from the claim text.