Automated systems for sterility testing of pharmaceutical fluid products

A testing assembly for automated sterility testing of pharmaceutical fluids, the assembly comprising:

• a set of one or more pumps;
• at least one plug actuator;
• and
• one or more processors having memory, the memory storing instructions, the one or more processors being configured to execute the instructions stored by the memory, the instructions, when executed by the one or more processors, causing:
• at least one pump of the set of one or more pumps to draw pharmaceutical fluid from a first container into a fluid inlet of a test container via tubing,
• wherein the tubing fluidly couples a needle to the fluid inlet of the test container, the needle being configured to pierce a closure of the first container, the test container being configured to receive the pharmaceutical fluid and bacterial growth media to facilitate testing sterility of the pharmaceutical fluid;
• one or more pumps of the set of one or more pumps to draw the pharmaceutical fluid out of a fluid outlet of the test container;
• the one or more processors to determine that the one or more pumps of the set of one or more pumps finished drawing the pharmaceutical fluid into the fluid inlet of the test container;
• the at least one pump to draw a rinsing fluid into the fluid inlet of the test container based on the determination that drawing the pharmaceutical fluid is finished;
• the one or more processors to determine that the at least one pump is finished drawing the rinsing fluid into the fluid inlet of the test container;
• the at least one plug actuator to couple a plug to the fluid outlet of the test container based on the determination that drawing the rinsing fluid is finished;
• the one or more processors to determine that the at least one plug actuator coupled the plug to the fluid outlet of the test container;
• and
• the at least one pump to draw the bacterial growth media into the fluid inlet of the test container based on the determination that the plug is coupled to the fluid outlet of the test container,
• whereby the at least one plug actuator coupling the plug to the fluid outlet of the test container prevents the growth media from draining out of the test container while drawing the growth media into the test container, thereby facilitating testing the sterility of the pharmaceutical fluid.