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US 12,716,086 B2Granted
Acrylate derivatives and uses thereof
AssigneeExpansion Technologies
InventorMahender Babu Dewal
Life of this patent
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Abstract
This disclosure relates to new cross-linking reagents for incorporating proteins and nucleic acids into polyelectrolyte gels, for use in expansion microscopy and other methods.
Claims9
A compound of Formula IIA or IIB:
- wherein Z is selected from among:
- wherein
- each occurrence of n is independently 1, 2, 3, 4, 5, 6, 7 or 8;
- R is selected from hydrogen, deuterium, halo, —CN, —NO2, and an optionally substituted aliphatic, alicyclic, heteroaliphatic, heterocyclic, aromatic, acyl or heteroaromatic group;
- and
- R1, R2 and R3 are independently H, alkyl, acyl or allyl.
3 more elements
Dependencies are inferred from the claim text.