Jet injection system

A microfluidic device (100) comprising a hosting chamber (110) defined by a chamber wall (120), wherein the hosting chamber (110) is configured to host a liquid (50), wherein at least part of the chamber wall (120) is light transmissive for laser radiation (201), the hosting chamber (110) having a chamber height c selected from a range of 80-120 μm, a chamber width wc selected from a range of 3hc-4.5hc or from a range of 5.5hc-6hc, and a chamber length lc defined by a first chamber end (111) and a second chamber end (112), wherein along at least 80% of the chamber length lc the chamber height hc and chamber width wc are constant, wherein one or both of the chamber height hc and chamber width wc vary with less than 10% relative to respective maximum values, and wherein along at least 80% of the chamber legnth lc the hosting chamber (110) has a cross-sectional shape selected from the group consisting of a rounded rectangle, a stadium, and an oval, wherein the second chamber end (112) comprises a first chamber opening (131) for jet ejection from the hosting chamber (110).