Fluidized bed granulation and coating systems and methods
AssigneesPurdue Research Foundation, Eli Lilly and Company
InventorsPaul R. Mort, Line Koleilat, Jonathan Wade, Joshua Hanson
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AssigneesPurdue Research Foundation, Eli Lilly and Company
InventorsPaul R. Mort, Line Koleilat, Jonathan Wade, Joshua Hanson
Estimating the term…
A fluidized bed granulation (FBG) system includes a pre-wetting subsystem, wherein feedstock is pre-wet to a predetermined % value, a fluidization chamber (FC), an inlet coupled to the FC, a plenum coupled to the FC by a distributor plate having slots through which a fluidization gas is passed to the FC at a velocity and a direction, an outlet compartment coupled to the FC by a termination plate having one or more filter bags, a liquid binder system adapted to introduce a liquid binder into the FC, and an outlet configured to eject granulated product, and a plurality of sensors adapted to inform a processor executing instructions maintained on a non-transitory memory, wherein the processor using a mass, energy, and fluidization balance model is adapted to optimize the FBG system to provide the granulated product having an optimized geometric mean and geometric standard deviation between about 2.0 and about 1.0.
A fluidized bed granulation (FBG) system, comprising:
Dependencies are inferred from the claim text.