# US 12,714,851 B1 · Systems, devices, and methods for inserting arrays

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- Number: US 12,714,851 B1
- Document ID: US12714851B1
- Status: Granted
- Kind: B1
- Application number: 18/806,233
- Filed: 2024-08-15
- Granted: 2026-08-25
- Earliest claimed: 2023-08-17
- Assignees: Paradromics, Inc.
- Applicants: Paradromics, Inc.
- Inventors: Michael E. Landry; James Burrows; Robert James Jones
- Web page: https://patentgrep.com/patent/US12714851B1

## CPC

- A61N 1/0531: {Brain cortex electrodes}
- A61N 1/0539: {Anchoring of brain electrode systems, e.g. within burr hole}
- A61N 1/0529: {Electrodes for brain stimulation}
- A61N 1/0534: {Electrodes for deep brain stimulation}
- A61N 1/372: Arrangements in connection with the implantation of stimulators
- A61N 1/37205: {Microstimulators, e.g. implantable through a cannula}
- A61N 1/37514: {Brain implants}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

In some aspects, the present disclosure provides a device for inserting an implant into a tissue in the central nervous system of a subject. In some embodiments, the device includes an implant support in mechanical communication with an implant. In some embodiments, the device includes a propulsion mechanism configured to propel the implant towards the tissue at a first time. In some embodiments, the device includes a triggering mechanism configured to activate a retraction mechanism at a second time, wherein the retraction mechanism is configured to retract the implant support upon activation. In some embodiments, a duration of time elapsed between the first time and the second time is less than 200 milliseconds.

## Claims

### Claim 1

A device for inserting an implant into a tissue in the central nervous system of a subject, comprising:
(a) an implant support configured to be in mechanical communication with the implant;
(b) a propulsion mechanism configured to propel the implant towards the tissue at a first time; and
(c) a triggering mechanism configured to activate a retraction mechanism at a second time, wherein the retraction mechanism is configured to retract the implant support upon activation,
wherein a duration of time elapsed between the first time and the second time is less than about 200 milliseconds.

### Claim 2 (depends on 1)

The device of claim 1, wherein the propulsion mechanism comprises an internal energy source configured to propel the implant towards the tissue, wherein the internal energy source is within a sterile field of the device.

### Claim 3 (depends on 2)

The device of claim 2, wherein the propulsion mechanism does not require an energy source external to the sterile field of the device to propel the implant towards the tissue with a velocity sufficient to insert the implant into the tissue to a predetermined depth.

### Claim 4 (depends on 2)

The device of claim 2, wherein the internal energy source is contained within a housing of the device.

### Claim 5 (depends on 2)

The device of claim 2, wherein at least about 20% of a kinetic energy of the implant, when propelled, is provided from the internal energy source.

### Claim 6 (depends on 5)

The device of claim 5, wherein less than 20% of the kinetic energy of the implant, when propelled, is provided from an external energy source.

### Claim 7 (depends on 6)

The device of claim 6, wherein the external energy source comprises an external positive pressure source.

### Claim 8 (depends on 1)

The device of claim 1, wherein the retraction mechanism is configured to begin retraction of the implant support after the propulsion mechanism propels the implant towards the tissue at the first time.

### Claim 9 (depends on 1)

The device of claim 1, wherein the retraction mechanism is configured to begin retraction of the implant support before the propulsion mechanism propels the implant towards the tissue at the first time.

### Claim 10 (depends on 1)

The device of claim 1, wherein the retraction mechanism is configured to retract the implant support before the implant is inserted in the tissue of the central nervous system.

### Claim 11 (depends on 1)

The device of claim 1, wherein the triggering mechanism comprises ball bearings.

### Claim 12 (depends on 11)

The device of claim 11, wherein the triggering mechanism actuates via a change in the position of the ball bearings within the device.

### Claim 13 (depends on 1)

The device of claim 1, wherein the device is configured to avoid contacting the tissue or the implant after the implant is inserted into the tissue.

### Claim 14 (depends on 1)

The device of claim 1, further comprising a firing mechanism configured to activate the propulsion mechanism.

### Claim 15 (depends on 14)

The device of claim 14, wherein the firing mechanism comprises a firing turn key.

### Claim 16 (depends on 14)

The device of claim 14, wherein the firing mechanism is configured to prevent rotation of the propulsion mechanism upon firing.

### Claim 17 (depends on 1)

The device of claim 1, wherein the implant support comprises a gripping mechanism.

### Claim 18 (depends on 17)

The device of claim 17, wherein the gripping mechanism is configured to grip the implant when the device is in a first state, and wherein the gripping mechanism is configured to not grip the implant when the device is in a second state.

### Claim 19 (depends on 1)

The device of claim 1, wherein the implant support is configured to protect the implant from mechanical damage until the implant is inserted into the tissue of the subject.

### Claim 20 (depends on 1)

The device of claim 1, wherein the tissue is a neural tissue.
